Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31618280 | 0.86 | MAPT (0.63) | MAPTKMT2AMEN1GPR139CYP3A4 | |
| SCHEMBL23122282 | 0.86 | MAPT (0.63) | MAPTKMT2AMEN1GPR139CYP3A4 | |
| SCHEMBL6426547 | 0.86 | MAPT (0.63) | MAPTKMT2AMEN1GPR139CYP3A4 | |
| SCHEMBL6427169 | 0.86 | MAPT (0.63) | MAPTKMT2AMEN1GPR139CYP3A4 | |
| SCHEMBL3076773 | 0.84 | MAPT (0.71) | MAPTKMT2AMEN1GPR139CYP3A4 | |
| SCHEMBL16975095 | 0.84 | MAPT (0.71) | MAPTKMT2AMEN1GPR139CYP3A4 | |
| SCHEMBL692819 | 0.84 | MAPT (0.71) | MAPTKMT2AMEN1GPR139CYP3A4 | |
| SCHEMBL23080142 | 0.84 | MAPT (0.71) | MAPTKMT2AMEN1GPR139CYP3A4 | |
| SCHEMBL3069332 | 0.84 | MAPT (0.71) | MAPTKMT2AMEN1GPR139CYP3A4 | |
| SCHEMBL18241727 | 0.84 | MAPT (0.71) | MAPTKMT2AMEN1GPR139CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793414-B | The synthetic method of (S, S) -2,8- diazabicyclo [4.3.0] nonane | 上虞京新药业有限公司 | 2019-07-23 | — | — | CN | disclosed |