Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8793014 | 0.77 | MAPT (0.45) | PRKCZMAPTMAPK8MAPK9MAPK10 | |
| SCHEMBL20263513 | 0.72 | TSHR (0.39) | PRKCZMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL17398237 | 0.71 | NOTUM (0.46) | PRKCZMAPTMAPK8MAPK10CA12 | |
| SCHEMBL31729716 | 0.71 | KDM4E (0.41) | MAPTKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL3306728 | 0.71 | KMT2A (0.41) | MAPTKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL9544732 | 0.71 | CA12 (0.55) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL4074676 | 0.69 | CA12 (0.48) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL24716081 | 0.69 | KMT2A (0.47) | PRKCZMAPTCA12CA1CA2 | |
| SCHEMBL20263506 | 0.68 | MAPK8 (0.41) | MAPTMAPK8MAPK9MAPK10CA12 | |
| SCHEMBL1649000 | 0.68 | CA12 (0.43) | PRKCZMAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099907-A | The Thienopyrroles derivative of targeting protein, composition, method and application thereof | 拜欧赛里克斯公司 | 2019-08-06 | — | — | CN | disclosed |