Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844679 | 0.88 | MAPT (0.56) | TSHRMAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL9913544 | 0.82 | MAPT (0.53) | TSHRMAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL2551921 | 0.82 | TDP1 (0.53) | TSHRMAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL2654454 | 0.81 | TDP1 (0.51) | TSHRMAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL29277905 | 0.80 | MAPT (0.47) | TSHRMAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL15157040 | 0.80 | MAPT (0.50) | TSHRMAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL3737931 | 0.79 | MAPT (0.48) | TSHRMAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL28314138 | 0.76 | MAPT (0.46) | TSHRMAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL13041548 | 0.76 | TSHR (0.44) | TSHRMAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL9913420 | 0.76 | TDP1 (0.56) | TSHRMAPTTDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036002-A | Medical compounds | 细胞中心有限公司 | 2019-07-19 | — | — | CN | disclosed |