SCHEMBL28313504

SCHEMBL28313504

CN(C)CCC[C@](O)(c1ccc(F)cc1)c1ccccc1CO

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 8/20 0.52
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
ADRA1A P35348 1/20 0.46
OPRK1 P41145 1/20 0.46
KCNH2 Q12809 1/20 0.46
LMNA P02545 1/20 0.45
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM5 P08912 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRM3 P20309 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GAA P10253 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SIGMAR1 Q99720 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28313502 1.00 BCL2 (0.52) BCL2HTR2AHTR2CADRA1AOPRK1
SCHEMBL27878319 0.95 BCL2 (0.48) BCL2HTR2AHTR2CADRA1AOPRK1
Bromide SCHEMBL27635599 0.94 BCL2 (0.47) BCL2HTR2AHTR2CADRA1AOPRK1
Cyanide SCHEMBL28313506 0.93 BCL2 (0.45) BCL2HTR2AHTR2CADRA1AOPRK1
SCHEMBL23333193 0.85 BCL2 (0.46) BCL2HTR2AHTR2CADRA1AOPRK1
SCHEMBL7411077 0.84 BCL2 (0.45) BCL2HTR2AHTR2CADRA1AOPRK1
SCHEMBL6414489 0.84 BCL2 (0.45) BCL2HTR2AHTR2CADRA1AOPRK1
SCHEMBL28444599 0.84 BCL2 (0.58) BCL2HTR2AHTR2CADRA1AOPRK1
SCHEMBL2074588 0.84 BCL2 (0.45) BCL2HTR2AHTR2CADRA1AOPRK1
SCHEMBL14646386 0.84 BCL2 (0.42) BCL2HTR2AHTR2CADRA1AOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109988083-A The preparation method of high-optical-purity escitalopram oxalate intermediate S configuration glycol 北京哈三联科技有限责任公司 2019-07-09 CN claimed
CN-109988083-A The preparation method of high-optical-purity escitalopram oxalate intermediate S configuration glycol 北京哈三联科技有限责任公司 2019-07-09 CN disclosed