Methylmalonic Acid

Methylmalonic Acid

SCHEMBL28314718

CC(C(=O)O)C(=O)O.[KH].[LiH]

nearest known ligand 0.85

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.50
SLC7A5 Q01650 2/20 0.40
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
RECQL P46063 1/20 0.35
GABRR1 P24046 2/20 0.35
RNPEP Q9H4A4 1/20 0.35
CYP1A2 P05177 1/20 0.35
ABCB11 O95342 1/20 0.33
F2 P00734 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylmalonic Acid SCHEMBL105829 0.96
Methylmalonic Acid SCHEMBL106057 0.96
Methylmalonic Acid SCHEMBL28315723 0.92 TP53 (0.50) TP53SLC7A5ALDH1A1TSHRLMNA
Methylmalonic Acid SCHEMBL28315758 0.92 TP53 (0.50) TP53SLC7A5ALDH1A1TSHRLMNA
Methylmalonic Acid SCHEMBL29072902 0.92 TP53 (0.50) TP53SLC7A5ALDH1A1TSHRLMNA
Methylmalonic Acid SCHEMBL27766 0.92
Methylmalonic Acid SCHEMBL27881917 0.92 TP53 (0.57) TP53SLC7A5ALDH1A1TSHRLMNA
Methylmalonic Acid SCHEMBL11586861 0.88
Methylmalonic Acid SCHEMBL10461696 0.88
Methylmalonic Acid SCHEMBL29018402 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110172019-A The metal salt of malonic acid as the nucleating additive for crystalline thermoplastic 印度石油有限公司 2019-08-27 CN disclosed