Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5119796 | 1.00 | HDAC1 (0.73) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28315091 | 0.96 | HDAC1 (0.72) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5121808 | 0.96 | HDAC1 (0.72) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5117358 | 0.88 | HDAC1 (0.74) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5123167 | 0.88 | HDAC1 (0.73) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28316246 | 0.86 | HDAC1 (0.77) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5125031 | 0.86 | HDAC1 (0.77) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5118367 | 0.86 | HDAC1 (0.79) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28876051 | 0.86 | HDAC1 (0.79) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5129606 | 0.86 | HDAC1 (0.71) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110063951-A | Improve the Compounds and methods for of impaired endogenous fibrinolysis using histone deacetylase mortifier | 赛伦诺科学有限公司 | 2019-07-30 | — | — | CN | disclosed |