Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5127746 | 1.00 | HDAC1 (0.59) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL5130136 | 0.86 | HDAC1 (0.59) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL28316169 | 0.86 | HDAC1 (0.59) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL14254988 | 0.77 | HDAC1 (0.61) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL14254913 | 0.77 | HDAC1 (0.61) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL14254912 | 0.76 | HDAC1 (0.57) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL5119289 | 0.75 | HDAC1 (0.66) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL15513503 | 0.75 | HDAC1 (1.00) | HDAC1HDAC4HDAC3HDAC2HDAC6 | |
| SCHEMBL14254985 | 0.74 | HDAC1 (0.71) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL8337680 | 0.74 | HDAC1 (0.71) | HDAC1HDAC4HDAC3HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110063951-A | Improve the Compounds and methods for of impaired endogenous fibrinolysis using histone deacetylase mortifier | 赛伦诺科学有限公司 | 2019-07-30 | — | — | CN | disclosed |