Butyric Acid

Butyric Acid

SCHEMBL28317752

CCC(Oc1ccc(Cl)cc1Cl)C(=O)O.CCCC(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.59
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
POLB P06746 1/20 0.53
GAA P10253 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.49
TDP1 Q9NUW8 2/20 0.48
PTGDR2 Q9Y5Y4 1/20 0.47
TSHR P16473 1/20 0.47
FFAR1 O14842 2/20 0.46
PPARG P37231 3/20 0.45
RAB9A P51151 1/20 0.44
RECQL P46063 1/20 0.43
HTT P42858 1/20 0.43
HPGD P15428 2/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL541271 0.92 PPARA (0.68) PPARACYP1A2CYP2C9CYP2C19POLB
SCHEMBL9780844 0.92 PPARA (0.68) PPARACYP1A2CYP2C9CYP2C19POLB
SCHEMBL31414363 0.90 PPARA (0.66) PPARACYP1A2CYP2C9CYP2C19POLB
SCHEMBL28921965 0.90 PPARA (0.66) PPARACYP1A2CYP2C9CYP2C19POLB
SCHEMBL10875112 0.83 PPARA (0.64) PPARACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL29076634 0.82 PPARA (0.63) PPARACYP1A2CYP2C9CYP2C19POLB
SCHEMBL1565785 0.81 PPARA (0.61) PPARACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL30100912 0.81 PPARA (0.57) PPARACYP1A2CYP2C9CYP2C19POLB
Butyric Acid SCHEMBL28317751 0.81 TDP1 (0.53) CYP1A2CYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL11212441 0.80 POLB (0.63) PPARAPOLBGAASMN1; SMN2PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110114456-A Novel acyltransferase, variant thioesterase and its purposes 柯碧恩生物技术公司 2019-08-09 CN disclosed