Oxirane

Oxirane

SCHEMBL28319014

C1CO1.CCCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
THRB P10828 1/20 0.61
EPHX1 P07099 1/20 0.48
ALDH1A1 P00352 4/20 0.46
DNM1 Q05193 6/20 0.44
LMNA P02545 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HSD17B10 Q99714 1/20 0.44
SLC22A1 O15245 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptane SCHEMBL11316948 1.00 TSHR (0.61) TSHRTHRBEPHX1ALDH1A1DNM1
Oxirane SCHEMBL28247935 1.00 TSHR (0.61) TSHRTHRBEPHX1ALDH1A1DNM1
Octane SCHEMBL28172325 1.00 TSHR (0.61) TSHRTHRBEPHX1ALDH1A1DNM1
Oxirane SCHEMBL28436205 1.00 TSHR (0.61) TSHRTHRBEPHX1ALDH1A1DNM1
Tetradecane SCHEMBL28284620 0.96 TSHR (0.57) TSHRTHRBEPHX1ALDH1A1DNM1
Decane SCHEMBL4618626 0.96 TSHR (0.57) TSHRTHRBEPHX1ALDH1A1DNM1
Nonane SCHEMBL27725295 0.96 TSHR (0.57) TSHRTHRBEPHX1ALDH1A1DNM1
Heptane SCHEMBL1803195 0.96 TSHR (0.57) TSHRTHRBEPHX1ALDH1A1DNM1
Dioxane SCHEMBL29286326 0.96 TSHR (0.57) TSHRTHRBEPHX1ALDH1A1DNM1
Hexane SCHEMBL5207457 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110266256-B System and method for generating power and reducing water evaporation 中国水利水电科学研究院 2020-11-13 CN disclosed
CN-210684595-U System for preventing reservoir evaporation by utilizing graphite powder 中国水利水电科学研究院 2020-06-05 CN disclosed
CN-110266256-A A kind of system and method taken into account power generation and reduce moisture evaporation 中国水利水电科学研究院 2019-09-20 CN disclosed
CN-110258438-A A kind of system preventing reservoir evaporation using graphite powder 中国水利水电科学研究院 2019-09-20 CN disclosed