Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.55 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29796894 | 0.85 | BRAF (0.54) | KCNA5FABP4BRAFCYP2C9 | |
| SCHEMBL855793 | 0.85 | BRAF (0.54) | KCNA5FABP4BRAFCYP2C9 | |
| SCHEMBL27101339 | 0.83 | — | — | |
| SCHEMBL913263 | 0.81 | BRAF (0.46) | FABP4BRAFACLY | |
| SCHEMBL28320106 | 0.81 | — | — | |
| SCHEMBL20399212 | 0.79 | BRAF (0.46) | KCNA5FABP4BRAFCYP2C9 | |
| SCHEMBL20399271 | 0.77 | KMT2A (0.55) | FABP4ALDH1A1HSD17B10 | |
| SCHEMBL856018 | 0.74 | BRAF (0.57) | KCNA5BRAFCYP2C9 | |
| SCHEMBL411593 | 0.73 | BRAF (0.53) | KCNA5BRAFCYP2C9 | |
| SCHEMBL9930242 | 0.73 | BRAF (0.53) | KCNA5BRAFALDH1A1HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110291089-A | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death | 海帕瑞吉尼克斯股份有限公司 | 2019-09-27 | — | — | CN | disclosed |