Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1359627 | 0.96 | KMT2A (0.50) | KMT2AKEAP1ALDH1A1NQO1MAPT | |
| Ethylene SCHEMBL2040209 | 0.92 | KMT2A (0.47) | KMT2AKEAP1ALDH1A1NQO1MAPT | |
| SCHEMBL28689938 | 0.88 | KMT2A (0.47) | KMT2AKEAP1ALDH1A1NQO1MAPT | |
| SCHEMBL1556391 | 0.75 | MAPT (0.39) | KMT2AKEAP1ALDH1A1MAPTHTT | |
| SCHEMBL28880373 | 0.74 | KMT2A (0.51) | KMT2AALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL13283367 | 0.74 | — | — | |
| SCHEMBL4582641 | 0.74 | — | — | |
| SCHEMBL1556823 | 0.73 | CYP1A2 (0.44) | KMT2AALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL15989455 | 0.72 | — | — | |
| SCHEMBL7013911 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218298-B | Soluble thiophene copolymer and preparation method and application thereof | 华东师范大学 | 2021-12-24 | — | — | CN | disclosed |
| CN-110218298-A | A kind of solubility thiophene copolymers and its preparation method and application | 华东师范大学 | 2019-09-10 | — | — | CN | disclosed |