Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321728 | 0.85 | SRD5A2 (0.42) | SRD5A2NR1H2NR1H3SRD5A1MAOB | |
| SCHEMBL28876791 | 0.82 | NR1H2 (0.40) | NR1H2NR1H3MRGPRX4 | |
| SCHEMBL28876730 | 0.79 | SRD5A2 (0.44) | SRD5A2NR1H2NR1H3SRD5A1LMNA | |
| SCHEMBL28320545 | 0.78 | IDO1 (0.58) | SRD5A2NR1H2MRGPRX4 | |
| SCHEMBL16399235 | 0.77 | NR1H2 (0.42) | SRD5A2NR1H2NR1H3SRD5A1LMNA | |
| SCHEMBL16398186 | 0.76 | NR1H2 (0.40) | SRD5A2NR1H2NR1H3SRD5A1LMNA | |
| SCHEMBL21945695 | 0.76 | NR1H2 (0.40) | SRD5A2NR1H2NR1H3SRD5A1LMNA | |
| SCHEMBL5020244 | 0.75 | SCN2A (0.56) | SCN2A | |
| SCHEMBL21945003 | 0.73 | SRD5A2 (0.47) | SRD5A2NR1H2NR1H3SRD5A1LMNA | |
| SCHEMBL16398920 | 0.73 | NPC1 (0.52) | SRD5A2SRD5A1POLBL3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |