Oxirane

Oxirane

SCHEMBL28320649

C1CO1.C=CCOC(=O)CC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
TDP1 Q9NUW8 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.38
PKM P14618 1/20 0.38
ALDH1A1 P00352 8/20 0.36
GAA P10253 1/20 0.36
CYP3A4 P08684 1/20 0.36
NPSR1 Q6W5P4 2/20 0.36
NAAA Q02083 1/20 0.35
MAPT P10636 1/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
HPGD P15428 5/20 0.34
KDM4E B2RXH2 4/20 0.34
HSD17B10 Q99714 4/20 0.34
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dioxane SCHEMBL28165359 0.98 TSHR (0.49) TSHRTDP1SMN1; SMN2PKMALDH1A1
SCHEMBL194711 0.89
Cyclohexane SCHEMBL393519 0.88 TSHR (0.53) TSHRTDP1SMN1; SMN2PKMALDH1A1
Ammonia Solution, Strong SCHEMBL4793964 0.87
Hydrochloric Acid SCHEMBL27874012 0.87
Water SCHEMBL28111613 0.87
Methane SCHEMBL27480384 0.87
Ethylene SCHEMBL7133194 0.87 TSHR (0.57) TSHRTDP1SMN1; SMN2PKMALDH1A1
SCHEMBL28165360 0.87 TSHR (0.46) TSHRTDP1SMN1; SMN2PKMALDH1A1
Propene SCHEMBL27611114 0.85 TSHR (0.55) TSHRTDP1SMN1; SMN2PKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110256632-A A kind of preparation method of chromium-free highly -branched degree polyolefin resin 中韩(武汉)石油化工有限公司 2019-09-20 CN disclosed