Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320840 | 0.85 | GRIN2D (0.57) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL30508946 | 0.79 | GRIN2D (0.57) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL1261302 | 0.78 | GRIN2D (0.65) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| Eticyclidine SCHEMBL7258514 | 0.77 | GRIN2D (0.51) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL28573222 | 0.77 | GRIN2D (0.59) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL27561886 | 0.77 | GRIN2D (0.62) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL30534232 | 0.77 | GRIN2D (0.62) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL29604371 | 0.77 | GRIN2D (0.62) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL28389473 | 0.76 | GRIN2D (0.48) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL28391948 | 0.75 | GRIN2D (0.56) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110172058-B | 7-azaspiro [5.6] dodecane-10-one compound and preparation method and application thereof | 中国医科大学 | 2021-06-04 | — | — | CN | claimed |
| CN-110172058-B | 7-azaspiro [5.6] dodecane-10-one compound and preparation method and application thereof | 中国医科大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-110172058-A | 7- azaspiro [5.6] dodecane -10- ketone compounds and preparation method thereof and purposes | 中国医科大学 | 2019-08-27 | — | — | CN | disclosed |