Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28876772 | 0.84 | TACR1 (0.37) | FFAR4TACR1SLC6A4HTR2AHTR2B | |
| SCHEMBL16398927 | 0.80 | FFAR4 (0.38) | PPARGPPARAFFAR4PTPN1RXRA | |
| SCHEMBL31144931 | 0.73 | IKBKB (0.37) | PPARGRXRARXRBRXRGRAB9A | |
| SCHEMBL28320827 | 0.73 | PPARG (0.68) | PPARGPPARASLC6A4HTR2AHTR2B | |
| SCHEMBL28320549 | 0.72 | PARP14 (0.38) | PDE4BNPSR1LMNAMAPT | |
| SCHEMBL16398724 | 0.72 | PPARG (0.44) | PPARGPPARAFFAR4TACR1RXRA | |
| SCHEMBL16399237 | 0.72 | PPARG (0.47) | PPARGPPARATACR1SLC6A4HTR2A | |
| SCHEMBL28876729 | 0.70 | MRGPRX4 (0.44) | — | |
| SCHEMBL28320562 | 0.69 | MAOB (0.35) | RXRARXRBRXRG | |
| SCHEMBL5612780 | 0.68 | IDO1 (0.54) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |