Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 5/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27470501 | 0.80 | CHRNA7 (0.43) | SLC6A2SLC6A4BCHESLC6A3LMNA | |
| SCHEMBL28315283 | 0.73 | SCN1A (0.45) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13162864 | 0.71 | CHEK1 (0.56) | SSTR4SLC6A2SLC6A4MAPT | |
| SCHEMBL9207735 | 0.71 | SSTR4 (0.38) | SSTR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2574276 | 0.71 | KDM4E (0.40) | BCHEMAPT | |
| SCHEMBL322584 | 0.70 | TAAR1 (0.50) | — | |
| SCHEMBL14256169 | 0.70 | MAPT (0.47) | SLC6A2SLC6A4BCHESLC6A3PKM | |
| SCHEMBL27929943 | 0.70 | SCN1A (0.50) | BCHEPKM | |
| Hydrochloric Acid SCHEMBL23277053 | 0.70 | SSTR4 (0.37) | SSTR4SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL20599528 | 0.70 | SSTR4 (0.37) | SSTR4SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283454-B | Quinazoline and azepine quinazoline as RAS/RAF/MEK/ERK and PI3K/AKT/PTEN/MTOR access double inhibitor | ASANA BIOSCIENCES, LLC (US) | 2019-10-29 | — | — | CN | disclosed |