Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 13/20 | 0.75 |
| ▸ | LCK | P06239 | 9/20 | 0.75 |
| ▸ | BTK | Q06187 | 10/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096781 | 0.86 | JAK3 (0.59) | JAK3LCKBTKEGFR | |
| SCHEMBL28322914 | 0.86 | JAK3 (0.59) | JAK3LCKBTKEGFR | |
| SCHEMBL16763728 | 0.86 | JAK3 (1.00) | JAK3LCKBTKEGFR | |
| SCHEMBL16764347 | 0.86 | JAK3 (1.00) | JAK3LCKBTKEGFR | |
| SCHEMBL28324045 | 0.86 | BTK (0.64) | JAK3LCKBTKEGFR | |
| SCHEMBL28322931 | 0.86 | BTK (0.64) | JAK3LCKBTKEGFR | |
| SCHEMBL28322911 | 0.81 | BTK (0.72) | JAK3LCKBTKEGFR | |
| SCHEMBL28322916 | 0.80 | JAK3 (0.72) | JAK3LCKBTKEGFR | |
| SCHEMBL28323056 | 0.79 | BTK (0.75) | JAK3LCKBTKEGFR | |
| SCHEMBL28324056 | 0.78 | JAK3 (0.62) | JAK3LCKBTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960404-B | The inhibitor of bruton's tyrosine kinase | 药品循环有限责任公司 | 2019-09-03 | — | — | CN | claimed |