Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 8/20 | 0.72 |
| ▸ | LCK | P06239 | 8/20 | 0.72 |
| ▸ | EGFR | P00533 | 3/20 | 0.58 |
| ▸ | BTK | Q06187 | 9/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16763896 | 0.84 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL16764241 | 0.84 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL28323999 | 0.83 | LCK (0.70) | JAK3LCKEGFRBTK | |
| SCHEMBL28324045 | 0.81 | BTK (0.64) | JAK3LCKEGFRBTK | |
| SCHEMBL28322931 | 0.81 | BTK (0.64) | JAK3LCKEGFRBTK | |
| SCHEMBL23081038 | 0.79 | JAK3 (0.90) | JAK3LCKEGFRBTK | |
| SCHEMBL28322911 | 0.77 | BTK (0.72) | JAK3LCKEGFRBTK | |
| SCHEMBL28322924 | 0.76 | JAK3 (0.57) | JAK3LCKEGFRBTK | |
| SCHEMBL28322916 | 0.76 | JAK3 (0.72) | JAK3LCKEGFRBTK | |
| SCHEMBL28322957 | 0.75 | BTK (0.70) | JAK3LCKEGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960404-B | The inhibitor of bruton's tyrosine kinase | 药品循环有限责任公司 | 2019-09-03 | — | — | CN | disclosed |