Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15717118 | 0.94 | OR51E2 (0.53) | OR51E2GPR84FFAR1SMN1; SMN2TET2 | |
| SCHEMBL15355768 | 0.94 | — | — | |
| SCHEMBL264859 | 0.94 | — | — | |
| SCHEMBL6963 | 0.94 | — | — | |
| SCHEMBL193026 | 0.94 | — | — | |
| Lactic Acid SCHEMBL27340731 | 0.92 | TP53 (0.55) | OR51E2GPR84FFAR1SMN1; SMN2TET2 | |
| Ethylene Glycol SCHEMBL15655041 | 0.92 | OR51E2 (0.52) | OR51E2GPR84FFAR1SMN1; SMN2TET2 | |
| SCHEMBL19434139 | 0.91 | — | — | |
| Bicarbonate SCHEMBL21899730 | 0.91 | OR51E2 (0.50) | OR51E2GPR84FFAR1SMN1; SMN2TET2 | |
| SCHEMBL11666742 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110344250-A | A kind of conductive fabric for clothes of losing weight, reduce weight | 尹淑珍 | 2019-10-18 | — | — | CN | disclosed |