Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Carvacrol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.84 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.84 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.84 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carvacrol SCHEMBL5326397 | 0.92 | PTGS1 (1.00) | PTGS1TRPA1CACNA1CLMNATYR | |
| Carvacrol SCHEMBL29544247 | 0.92 | PTGS1 (1.00) | PTGS1TRPA1CACNA1CLMNATYR | |
| Carvacrol SCHEMBL24734 | 0.92 | PTGS1 (1.00) | PTGS1TRPA1CACNA1CLMNATYR | |
| Carvacrol SCHEMBL31732819 | 0.90 | PTGS1 (0.95) | PTGS1TRPA1CACNA1CLMNATYR | |
| Carvacrol SCHEMBL28865744 | 0.90 | PTGS1 (0.95) | PTGS1TRPA1CACNA1CLMNATYR | |
| Carvacrol SCHEMBL1668461 | 0.90 | PTGS1 (0.95) | PTGS1TRPA1CACNA1CLMNATYR | |
| Carvacrol SCHEMBL7075922 | 0.90 | PTGS1 (0.95) | PTGS1TRPA1CACNA1CLMNATYR | |
| Carvacrol SCHEMBL5030301 | 0.90 | PTGS1 (0.95) | PTGS1TRPA1CACNA1CLMNATYR | |
| Carvacrol SCHEMBL5031273 | 0.90 | PTGS1 (0.95) | PTGS1TRPA1CACNA1CLMNATYR | |
| Carvacrol SCHEMBL29049290 | 0.90 | PTGS1 (0.95) | PTGS1TRPA1CACNA1CLMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126466-A | Humidity-responsive edible polysaccharide-cyclodextrin metal organic frame preservative film and preparation method thereof | 上海交通大学 | 2023-11-28 | — | — | CN | claimed |
| CN-113115770-B | Fresh cut flower preservative | 河北农业大学 | 2022-09-23 | — | — | CN | claimed |
| CN-113115770-A | Fresh cut flower preservative | 河北农业大学 | 2021-07-16 | — | — | CN | claimed |
| CN-110226598-A | A kind of tea tree pest repellant of Extracts from Plant Recourses | 福鼎市匠心百年茶业有限公司 | 2019-09-13 | — | — | CN | claimed |
| CN-117126466-A | Humidity-responsive edible polysaccharide-cyclodextrin metal organic frame preservative film and preparation method thereof | 上海交通大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-116251077-A | Preparation method of carvacrol-loaded composite nano particles | 盐城工业职业技术学院 | 2023-06-13 | — | — | CN | disclosed |
| CN-111449187-B | Lactobacillus buchneri S-layer protein modified carvacrol/beta-cyclodextrin liposome and preparation method and antibacterial application thereof | 扬州大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-113115770-B | Fresh cut flower preservative | 河北农业大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-113115770-B | Fresh cut flower preservative | 河北农业大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-113115770-A | Fresh cut flower preservative | 河北农业大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-113115770-A | Fresh cut flower preservative | 河北农业大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-111449187-A | Lactobacillus buchneri S-layer protein modified carvacrol/β -cyclodextrin liposome and preparation method and antibacterial application thereof | 扬州大学 | 2020-07-28 | — | — | CN | disclosed |
| CN-110604762-A | Traditional Chinese medicine composition for treating kidney-type infectious bronchitis of poultry and preparation method thereof | 临沂金翠兽药有限公司 | 2019-12-24 | — | — | CN | disclosed |
| CN-110226598-A | A kind of tea tree pest repellant of Extracts from Plant Recourses | 福鼎市匠心百年茶业有限公司 | 2019-09-13 | — | — | CN | disclosed |