Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.64 |
| ▸ | JAK3 | P52333 | 15/20 | 0.53 |
| ▸ | LCK | P06239 | 10/20 | 0.53 |
| ▸ | EGFR | P00533 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16764628 | 0.86 | BTK (0.85) | BTKJAK3LCKEGFR | |
| SCHEMBL16763621 | 0.86 | BTK (0.85) | BTKJAK3LCKEGFR | |
| SCHEMBL28876900 | 0.81 | BTK (0.60) | BTKJAK3LCKEGFR | |
| SCHEMBL16798510 | 0.79 | BTK (0.75) | BTKJAK3LCKEGFR | |
| SCHEMBL16789703 | 0.79 | BTK (0.75) | BTKJAK3LCKEGFR | |
| SCHEMBL16763989 | 0.78 | BTK (1.00) | BTKJAK3LCKEGFR | |
| SCHEMBL16763986 | 0.78 | BTK (1.00) | BTKJAK3LCKEGFR | |
| SCHEMBL16763985 | 0.78 | BTK (1.00) | BTKJAK3LCKEGFR | |
| SCHEMBL16763983 | 0.78 | BTK (1.00) | BTKJAK3LCKEGFR | |
| SCHEMBL16764440 | 0.78 | BTK (1.00) | BTKJAK3LCKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960404-B | The inhibitor of bruton's tyrosine kinase | 药品循环有限责任公司 | 2019-09-03 | — | — | CN | claimed |