Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29004140 | 0.90 | TSHR (0.56) | TSHRALDH1A1CYP3A4TDP1POLB | |
| SCHEMBL31216393 | 0.90 | TSHR (0.56) | TSHRALDH1A1CYP3A4TDP1POLB | |
| SCHEMBL5051462 | 0.89 | TSHR (0.51) | TSHRALDH1A1CYP3A4TDP1POLB | |
| Acrylic Acid Methyl Ester SCHEMBL28221323 | 0.88 | TSHR (0.50) | TSHRALDH1A1CYP3A4TDP1POLB | |
| Acrylic Acid Methyl Ester SCHEMBL27827983 | 0.88 | TSHR (0.50) | TSHRALDH1A1CYP3A4TDP1POLB | |
| Acrylic Acid Methyl Ester SCHEMBL28456671 | 0.88 | TSHR (0.50) | TSHRALDH1A1CYP3A4TDP1POLB | |
| SCHEMBL29594909 | 0.87 | TSHR (0.59) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL30783027 | 0.87 | TSHR (0.56) | TSHRALDH1A1CYP3A4TDP1POLB | |
| Acrylic Acid SCHEMBL27544030 | 0.86 | TSHR (0.54) | TSHRALDH1A1CYP3A4TDP1POLB | |
| Butadiene SCHEMBL4607813 | 0.86 | TSHR (0.57) | TSHRALDH1A1CYP3A4TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110381925-A | The pharmaceutical preparation of phloroglucin and TRIMETHYL PHLOROGLUCINOL | 辛瑞克斯制药有限公司 | 2019-10-25 | — | — | CN | disclosed |