Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 7/20 | 0.49 |
| ▸ | CA2 | P00918 | 7/20 | 0.49 |
| ▸ | CA9 | Q16790 | 7/20 | 0.49 |
| ▸ | HLCS | P50747 | 4/20 | 0.48 |
| ▸ | GIGYF2 | Q6Y7W6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23124066 | 0.91 | TDP1 (0.74) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL29556007 | 0.91 | TDP1 (0.74) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL1720240 | 0.86 | TDP1 (0.76) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21186262 | 0.83 | TDP1 (0.51) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL14613009 | 0.82 | CA12 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL264799 | 0.81 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL8669526 | 0.80 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL10618585 | 0.80 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21175073 | 0.80 | TDP1 (0.62) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21488913 | 0.79 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110261521-B | Identification of carbonylated proteins | 北京大学 | 2022-01-18 | — | — | CN | claimed |
| CN-110261521-A | The identification of carbonylation protein | 北京大学 | 2019-09-20 | — | — | CN | claimed |
| CN-110261521-B | Identification of carbonylated proteins | 北京大学 | 2022-01-18 | — | — | CN | disclosed |