Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 13/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832631 | 0.93 | S1PR1 (0.43) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1336504 | 0.87 | S1PR1 (0.41) | S1PR1S1PR3S1PR5BDKRB1 | |
| SCHEMBL1336574 | 0.87 | S1PR1 (0.47) | S1PR1S1PR3S1PR5 | |
| SCHEMBL13263433 | 0.83 | S1PR1 (0.40) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1337948 | 0.83 | S1PR1 (0.40) | S1PR1S1PR3S1PR5BDKRB1 | |
| SCHEMBL1337953 | 0.82 | S1PR1 (0.46) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1336486 | 0.82 | S1PR1 (0.41) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1338376 | 0.82 | S1PR1 (0.38) | S1PR1S1PR3S1PR5BDKRB1 | |
| SCHEMBL1337688 | 0.81 | S1PR1 (0.41) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1338057 | 0.80 | S1PR1 (0.46) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081692-A1 | OXADIAZOLE DERIVATIVES AS SLPL RECEPTOR AGONISTS | ALMIRALL, S.A. (ES) | 2010-07-22 | — | — | WO | disclosed |