Benzene

Benzene

SCHEMBL28326432

c1ccc(C(=C(c2ccccc2)c2ccccc2)c2ccccc2)cc1.c1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.53
CES2 O00748 2/20 0.53
TSHR P16473 2/20 0.53
DAO P14920 1/20 0.53
NAPRT Q6XQN6 1/20 0.53
ALDH1A1 P00352 1/20 0.53
SNCA P37840 2/20 0.48
ESR1 P03372 1/20 0.48
F2 P00734 2/20 0.47
CYP3A4 P08684 2/20 0.47
MAPT P10636 2/20 0.47
BLM P54132 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
CA2 P00918 2/20 0.47
CA4 P22748 2/20 0.47
F10 P00742 1/20 0.47
F12 P00748 1/20 0.47
F7 P08709 1/20 0.47
F3 P13726 1/20 0.47
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67982 1.00 CES1 (0.53) CES1CES2TSHRDAONAPRT
SCHEMBL28901985 0.96 CES1 (0.50) CES1CES2TSHRDAONAPRT
SCHEMBL5498483 0.96 CES1 (0.50) CES1CES2TSHRDAONAPRT
Hydrogen Sulfide SCHEMBL28308053 0.96 CES1 (0.50) CES1CES2TSHRDAONAPRT
SCHEMBL29707474 0.96 CES1 (0.50) CES1CES2TSHRDAONAPRT
SCHEMBL28445093 0.96 CES1 (0.50) CES1CES2TSHRDAONAPRT
SCHEMBL9580190 0.96 CES1 (0.50) CES1CES2TSHRDAONAPRT
SCHEMBL28643562 0.96 CES1 (0.50) CES1CES2TSHRDAONAPRT
SCHEMBL27970663 0.96 CES1 (0.50) CES1CES2TSHRDAONAPRT
SCHEMBL28153002 0.96 CES1 (0.50) CES1CES2TSHRDAONAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111039920-B Chiral tetraphenylethylene and synthesis method thereof 山东大学 2021-01-12 CN disclosed
CN-111690005-A Sensing array with mitochondrial targeting and aggregation-induced emission effects and application of sensing array in cell identification 北京化工大学 2020-09-22 CN disclosed
CN-111039920-A Chiral tetraphenylethylene and synthesis method thereof 山东大学 2020-04-21 CN disclosed
CN-111039764-A Amphiphilic ethylene derivative and preparation method thereof 山东大学 2020-04-21 CN disclosed
CN-110283193-A A kind of fluorescent probe compounds and preparation method thereof with grinding solid luminescent property 福建师范大学 2019-09-27 CN disclosed