SCHEMBL283284

SCHEMBL283284

CC(=O)N[C@H]1CCCC[C@H]1NC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 4/20 0.52
PSEN2 P49810 4/20 0.52
APH1B Q8WW43 4/20 0.52
NCSTN Q92542 4/20 0.52
APH1A Q96BI3 4/20 0.52
PSENEN Q9NZ42 4/20 0.52
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 2/20 0.43
EPHX1 P07099 6/20 0.42
ATM Q13315 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NPSR1 Q6W5P4 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MAPT P10636 1/20 0.40
CYP3A4 P08684 1/20 0.40
EPHX2 P34913 1/20 0.40
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
OGA O60502 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL282958 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL282957 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14559367 0.91 PSEN1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL21282785 0.91 PSEN1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1901754 0.88 PSEN1 (0.45) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL23772197 0.85 EPHX1 (0.60) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL18724878 0.85 PSEN1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL16204597 0.85 EPHX1 (0.60) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL15278105 0.85 PSEN1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL23772463 0.85 EPHX1 (0.60) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077120-A1 PHOTORESISTS COMPRISING MULTI-AMIDE COMPONENT ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2012-03-29 US claimed
EP-2428842-A1 Photoresists comprising multi-amide component Rohm and Haas Electronic Materials LLC (US) 2012-03-14 EP claimed
US-8867005-B2 Display element and display device SHARP KABUSHIKI KAISHA (JP) 2014-10-21 US disclosed
US-8765309-B2 Electrochemical device KONICA MINOLTA HOLDINGS, INC. (JP) 2014-07-01 US disclosed
US-8765309-B2 Electrochemical device KONICA MINOLTA HOLDINGS, INC. (JP) 2014-07-01 US disclosed
US-20120077120-A1 PHOTORESISTS COMPRISING MULTI-AMIDE COMPONENT ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2012-03-29 US disclosed
EP-2428842-A1 Photoresists comprising multi-amide component Rohm and Haas Electronic Materials LLC (US) 2012-03-14 EP disclosed
US-20110143211-A1 ELECTROCHEMICAL DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2011-06-16 US disclosed
US-20110143211-A1 ELECTROCHEMICAL DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2011-06-16 US disclosed
US-20090161042-A1 Display element and display device SHARP KABUSHIKI KAISHA (JP) 2009-06-25 US disclosed