Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.45 |
| ▸ | HMGCR | P04035 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3317342 | 1.00 | TSHR (0.60) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL8412547 | 0.95 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL21484045 | 0.95 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL8413427 | 0.95 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL28214293 | 0.95 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL10886003 | 0.95 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL8413428 | 0.95 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL17965694 | 0.90 | TSHR (0.55) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL27216011 | 0.90 | TSHR (0.60) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL8410683 | 0.90 | TSHR (0.60) | TSHRALDH1A1TDP1PTPN7HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110386863-A | The method for being prepared with the reduced form halide that carbon-to-carbon unsaturated bond is reduced | 信越化学工业株式会社 | 2019-10-29 | — | — | CN | disclosed |