Pyridine

Pyridine

SCHEMBL28329414

C#N.Oc1ccc[nH]1.c1ccncc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
DAO P14920 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
MAPT P10636 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL28104080 0.94 NAPRT (0.41) NAPRTTSHRTDP1DAOHDAC8
Pyridine SCHEMBL28280122 0.92 NAPRT (0.39) NAPRTTSHRTDP1DAOHDAC8
Pyridine SCHEMBL28212944 0.92 NAPRT (0.39) NAPRTTSHRTDP1DAOHDAC8
Pyrimidine SCHEMBL28144502 0.85 DAO (0.37) DAOHDAC8HDAC6
SCHEMBL243709 0.78
SCHEMBL27560869 0.75
Hydrochloric Acid SCHEMBL20916879 0.75
SCHEMBL644897 0.72 DAO (0.37) DAOHDAC8HDAC6
Pyridine SCHEMBL3491229 0.69
Benzene SCHEMBL28228140 0.69 TSHR (0.75) NAPRTTSHRTDP1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106660957-B Process for preparing 4-alkoxy-3-hydroxypicolinic acid 美国陶氏益农公司 2019-11-29 CN disclosed