⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146593 | 0.94 | — | — | |
| Water SCHEMBL2395414 | 0.89 | — | — | |
| Methylene Chloride SCHEMBL1413436 | 0.80 | — | — | |
| SCHEMBL16187210 | 0.63 | — | — | |
| SCHEMBL590441 | 0.60 | — | — | |
| SCHEMBL27199206 | 0.60 | — | — | |
| SCHEMBL11854072 | 0.60 | — | — | |
| SCHEMBL148450 | 0.59 | — | — | |
| SCHEMBL11713088 | 0.59 | — | — | |
| SCHEMBL15545874 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539098-B | Difunctional HDAC6 inhibitor, synthesis method and application | 青岛大学 | 2024-05-24 | — | — | CN | claimed |
| CN-113754591-B | HDAC, JAK and BET three-target inhibitor and preparation method and application thereof | 山东大学 | 2024-01-05 | — | — | CN | claimed |
| CN-116655577-B | Flavone derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2023-11-14 | — | — | CN | claimed |
| CN-116655577-A | Flavone derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2023-08-29 | — | — | CN | claimed |
| CN-114181116-B | D-amino acid derivative aminopeptidase N inhibitor, and preparation method and application thereof | 山东中医药大学 | 2023-05-23 | — | — | CN | claimed |
| CN-115232130-A | APN and AKT double-target-point inhibitor and preparation method and application thereof | 山东大学 | 2022-10-25 | — | — | CN | claimed |
| CN-114539098-A | Difunctional HDAC6 inhibitor, synthesis method and application | 青岛大学 | 2022-05-27 | — | — | CN | claimed |
| CN-114181116-A | D-amino acid derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2022-03-15 | — | — | CN | claimed |
| CN-113754591-A | HDAC, JAK and BET three-target inhibitor and preparation method and application thereof | 山东大学 | 2021-12-07 | — | — | CN | claimed |
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | claimed |
| CN-114539098-B | Difunctional HDAC6 inhibitor, synthesis method and application | 青岛大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-113582911-B | Multi-target donepezil-hydroxamic acid compound, and preparation method and application thereof | 山东大学 | 2024-03-12 | — | — | CN | disclosed |
| CN-115232130-B | APN and AKT double-target inhibitor and preparation method and application thereof | 山东大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-113754591-B | HDAC, JAK and BET three-target inhibitor and preparation method and application thereof | 山东大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-116655577-B | Flavone derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2023-11-14 | — | — | CN | disclosed |
| CN-113582911-A | Multi-target donepezil-hydroxamic acid type compound and preparation method and application thereof | 山东大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-108218800-B | 1, 2, 3-triazole aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-110551067-B | Multi-target tacrine derivative and preparation method and application thereof | 山东大学 | 2020-09-08 | — | — | CN | disclosed |
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | disclosed |
| CN-110551067-A | Multi-target tacrine derivative and preparation method and application thereof | UNIV SHANDONG | 2019-12-10 | — | — | CN | disclosed |