Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 16/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 16/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470325 | 0.94 | S1PR1 (0.49) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2474987 | 0.88 | S1PR1 (0.45) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2473926 | 0.87 | S1PR1 (0.41) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2474335 | 0.87 | S1PR1 (0.32) | S1PR1S1PR3 | |
| SCHEMBL2833395 | 0.86 | S1PR1 (0.40) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2475990 | 0.86 | S1PR1 (0.40) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2475496 | 0.84 | S1PR1 (0.45) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2467453 | 0.83 | S1PR1 (0.36) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2467232 | 0.83 | S1PR1 (0.40) | S1PR1S1PR3S1PR5 | |
| SCHEMBL3461503 | 0.82 | S1PR1 (0.43) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010072352-A1 | 1, 2, 4 -OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE | ALMIRALL S.A. (ES) | 2010-07-01 | — | — | WO | disclosed |