SCHEMBL28334258

SCHEMBL28334258

Nc1ccc(N2CCOC(F)C2)nc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
ADK P55263 2/20 0.37
OGA O60502 1/20 0.37
ALDH1A1 P00352 4/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12235930 0.82 NR3C2 (0.45) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2744990 0.82 NR3C2 (0.45) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL12235349 0.82 NR3C2 (0.45) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL15653334 0.82 GRIN2D (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL15653332 0.82 GRIN2D (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL17076797 0.80 ADORA2A (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL15651193 0.80 ADORA2A (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL15651191 0.80 ADORA2A (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL15650218 0.78 GRIN2D (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL17076726 0.78 GRIN2D (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110467615-A Azolopyrimidines include its pharmaceutical composition and its preparation method and application SICHUAN KELUN BOTAI BIOMEDICAL CO LTD 2019-11-19 CN disclosed