SCHEMBL28337070

SCHEMBL28337070

O=C(O)c1ccc2c(c1O)Cc1ccccc1-2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.50
SRD5A2 P31213 2/20 0.50
PNMT P11086 1/20 0.47
HNF4A P41235 1/20 0.46
CYP2C9 P11712 1/20 0.46
TSHR P16473 1/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HTR7 P34969 2/20 0.46
HTR2B P41595 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP1A2 P05177 1/20 0.45
HPGD P15428 1/20 0.45
PPARG P37231 1/20 0.43
SRD5A1 P18405 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31158183 0.83 HSP90AA1 (0.50) HSP90AA1SRD5A2PNMTCYP2C9TSHR
SCHEMBL3720118 0.83 HSP90AA1 (0.50) HSP90AA1SRD5A2PNMTCYP2C9TSHR
SCHEMBL29638295 0.81 HSP90AA1 (0.67) HSP90AA1SRD5A2PNMTHNF4ACYP2C9
SCHEMBL67699 0.81 HSP90AA1 (0.67) HSP90AA1SRD5A2PNMTHNF4ACYP2C9
SCHEMBL31229252 0.81 HSP90AA1 (0.67) HSP90AA1SRD5A2PNMTHNF4ACYP2C9
Hydrochloric Acid SCHEMBL6755698 0.79 HSP90AA1 (0.65) HSP90AA1SRD5A2PNMTHNF4ACYP2C9
SCHEMBL21758198 0.79 HSP90AA1 (0.56) HSP90AA1SRD5A2PNMTHNF4ACYP2C9
SCHEMBL9161973 0.78 HSP90AA1 (0.49) HSP90AA1SRD5A2PNMTHNF4ACYP2C9
SCHEMBL21758199 0.78 HSP90AA1 (0.49) HSP90AA1SRD5A2PNMTCYP2C9TSHR
SCHEMBL11194388 0.78 HSP90AA1 (0.46) HSP90AA1SRD5A2PNMTCYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110612295-A Pyrazole-3-carboxylic acid amide derivative and pest control agent 组合化学工业株式会社 2019-12-24 CN disclosed