SCHEMBL28339137

SCHEMBL28339137

Nc1ccc(NC(=O)c2ccc(N)cc2C(F)(F)F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 7/20 0.59
MEN1 O00255 2/20 0.50
LMNA P02545 2/20 0.50
KMT2A Q03164 2/20 0.50
POLB P06746 2/20 0.50
KLKB1 P03952 1/20 0.50
PKM P14618 1/20 0.50
APEX1 P27695 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CRBN Q96SW2 1/20 0.49
AVPR2 P30518 1/20 0.49
GPR27 Q9NS67 1/20 0.49
JAK2 O60674 1/20 0.48
TYK2 P29597 1/20 0.48
SNCA P37840 1/20 0.46
TRPV1 Q8NER1 1/20 0.46
PTPRC P08575 1/20 0.46
MAPT P10636 2/20 0.46
RAB9A P51151 1/20 0.46
KCNK3 O14649 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29771708 1.00 PTGS1 (0.59) PTGS1MEN1LMNAKMT2APOLB
SCHEMBL23730425 0.98 PTGS1 (0.61) PTGS1MEN1LMNAKMT2APOLB
SCHEMBL24203599 0.90 PTGS1 (0.53) PTGS1MEN1LMNAKMT2APOLB
SCHEMBL679036 0.90 PTGS1 (0.52) PTGS1MEN1LMNAKMT2APOLB
SCHEMBL20468347 0.88 PTGS1 (0.72) PTGS1CRBNAVPR2GPR27PTPRC
SCHEMBL20468344 0.87 PTGS1 (0.56) PTGS1KLKB1CRBNAVPR2GPR27
SCHEMBL25141317 0.86 PTGS1 (0.56) PTGS1MEN1LMNAKMT2APOLB
SCHEMBL24203630 0.85 PTGS1 (0.54) PTGS1KLKB1CRBNAVPR2GPR27
SCHEMBL28908365 0.85 PTGS1 (0.54) PTGS1MEN1LMNAKMT2APOLB
SCHEMBL21391974 0.84 PTGS1 (0.52) PTGS1MEN1KMT2APOLBCRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117964895-A High-temperature-resistant transparent polyimide, polyimide film and preparation method thereof 华为技术有限公司 2024-05-03 CN claimed
CN-117964895-A High-temperature-resistant transparent polyimide, polyimide film and preparation method thereof 华为技术有限公司 2024-05-03 CN disclosed
CN-110628025-B Polyimide precursor, polyimide, and material for use in production thereof 宇部兴产株式会社 2022-07-12 CN disclosed
CN-110628025-A Polyimide precursor, polyimide, and material for use in preparation thereof 宇部兴产株式会社 2019-12-31 CN disclosed