⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2899858 | 0.82 | SSTR4 (0.46) | — | |
| SCHEMBL7400413 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL28000053 | 0.80 | SSTR4 (0.45) | — | |
| SCHEMBL337118 | 0.80 | — | — | |
| SCHEMBL8164385 | 0.80 | — | — | |
| SCHEMBL302768 | 0.80 | — | — | |
| SCHEMBL7320155 | 0.79 | SSTR4 (0.45) | — | |
| SCHEMBL7320391 | 0.78 | SSTR4 (0.37) | — | |
| SCHEMBL24576137 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL1609138 | 0.78 | SSTR4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11208397-B2 | Small molecule antagonists of sumo related modification of CRMP2 and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-12-28 | — | — | US | disclosed |
| EP-2560966-B1 | MULTISUBSTITUTED AROMATIC COMPOUNDS AS INHIBITORS OF THROMBIN | VERSEON INT CORPORATION (US) | 2021-01-06 | — | — | EP | disclosed |
| EP-3421036-B1 | MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON CORP (US) | 2020-11-18 | — | — | EP | disclosed |
| US-20200277271-A1 | SMALL MOLECULE ANTAGONISTS OF SUMO RELATED MODIFICATION OF CRMP2 AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2020-09-03 | — | — | US | disclosed |
| US-10653674-B2 | Multisubstituted aromatic compounds as inhibitors of thrombin | VERSEON CORPORATION (US) | 2020-05-19 | — | — | US | disclosed |
| CN-110269856-A | Inhibitor of the polysubstituted aromatic compounds as fibrin ferment | 维颂公司 | 2019-09-24 | — | — | CN | disclosed |
| CN-104940200-B | Inhibitor of the polysubstituted aromatic compounds as fibrin ferment | 维颂公司 | 2019-06-28 | — | — | CN | disclosed |
| US-20190142813-A1 | MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INTERNATIONAL CORPORATION | 2019-05-16 | — | — | US | disclosed |
| US-10251872-B2 | Multisubstituted aromatic compounds as serine protease inhibitors | VERSEON CORPORATION (US) | 2019-04-09 | — | — | US | disclosed |
| EP-3421036-A1 | MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS | Verseon Corporation (US) | 2019-01-02 | — | — | EP | disclosed |
| US-5164372-A | Treatment of respiratory disorders, inflammation, dermatitis | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0247482-B1 | HARDENED REAGENT COATINGS, AND PROCESSES FOR THE PREPARATION THEREOF | MILES INC. (US) | 1992-04-22 | — | — | EP | disclosed |
| US-5034376-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1991-07-23 | — | — | US | disclosed |
| EP-0394989-A2 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4935405-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4814342-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0266950-A2 | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1988-05-11 | — | — | EP | disclosed |
| EP-0247482-A2 | Hardened reagent coatings, and processes for the preparation thereof | MILES INC. (US) | 1987-12-02 | — | — | EP | disclosed |
| EP-0210084-A1 | Amides, processes for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1987-01-28 | — | — | EP | disclosed |
| US-4063952-A | PROTEINS | AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) | 1977-12-20 | — | — | US | disclosed |