Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637921 | 0.93 | CHRNA7 (0.53) | CHRNA7MEN1KMT2AGAAHTR3E | |
| SCHEMBL22101385 | 0.86 | CHRNA7 (0.54) | CHRNA7MEN1KMT2AGAAHTR3E | |
| SCHEMBL21886707 | 0.86 | CHRNA7 (0.54) | CHRNA7MEN1KMT2AGAAHTR3E | |
| SCHEMBL14461205 | 0.86 | CHRNA7 (0.54) | CHRNA7MEN1KMT2AGAAHTR3E | |
| SCHEMBL28262599 | 0.85 | BCHE (0.55) | CHRNA7MEN1KMT2AGAAF2 | |
| SCHEMBL13369465 | 0.83 | CHRNA7 (0.51) | CHRNA7MEN1KMT2AGAAHTR3E | |
| SCHEMBL12614061 | 0.83 | CHRNA7 (0.51) | CHRNA7MEN1KMT2AGAAHTR3E | |
| SCHEMBL11636361 | 0.82 | MEN1 (0.53) | CHRNA7MEN1KMT2AGAAHTR3E | |
| SCHEMBL4453290 | 0.82 | MEN1 (0.69) | CHRNA7MEN1KMT2AGAAHTR3E | |
| SCHEMBL1786140 | 0.82 | MEN1 (0.69) | CHRNA7MEN1KMT2AGAAHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881681-A | Substituted pyrrolo [2,3-d ] pyrimidines, their preparation and their therapeutic use | 赛诺菲 | 2024-04-12 | — | — | CN | disclosed |
| CN-114727991-A | Arylmethylene heterocyclic compounds as Kv1.3 potassium SHAKER channel blockers | D·E·萧尔研究有限责任公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-110621671-A | Benzofuran and benzothiophene derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-27 | — | — | CN | disclosed |