Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 2/20 | 0.48 |
| ▸ | JAK1 | P23458 | 2/20 | 0.48 |
| ▸ | TYK2 | P29597 | 2/20 | 0.48 |
| ▸ | JAK3 | P52333 | 2/20 | 0.48 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2440282 | 0.95 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL5368396 | 0.95 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL6128832 | 0.95 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL16903351 | 0.91 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL18084804 | 0.90 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL1841984 | 0.87 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL492951 | 0.87 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL540519 | 0.87 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL18084813 | 0.87 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL13547248 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110577490-B | Synthetic method of abamectin intermediate (2S,5S) -N-protecting group-5-hydroxy-2-piperidine formate | 山东安信制药有限公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-110577490-A | synthetic method of abamectin intermediate (2S,5S) -N-protecting group-5-hydroxy-2-piperidine formate | 齐鲁天和惠世制药有限公司 | 2019-12-17 | — | — | CN | disclosed |