Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30172872 | 0.91 | MEN1 (0.47) | MEN1KMT2AMAPTTP53KLK7 | |
| SCHEMBL20487840 | 0.91 | MEN1 (0.47) | MEN1KMT2AMAPTTP53KLK7 | |
| SCHEMBL28339643 | 0.86 | MEN1 (0.43) | MEN1KMT2AMAPTTP53KLK7 | |
| SCHEMBL20487282 | 0.86 | MEN1 (0.49) | MEN1KMT2AMAPTTP53KLK7 | |
| SCHEMBL20486099 | 0.86 | MEN1 (0.51) | MEN1KMT2AMAPTTP53KLK7 | |
| SCHEMBL23959847 | 0.85 | MEN1 (0.42) | MEN1KMT2AMAPTTP53KLK7 | |
| SCHEMBL20486088 | 0.85 | KMT2A (0.41) | MEN1KMT2AMAPTTP53KLK7 | |
| SCHEMBL20487092 | 0.82 | TP53 (0.66) | MEN1KMT2AMAPTTP53TDP1 | |
| SCHEMBL20487636 | 0.82 | MEN1 (0.53) | MEN1KMT2AMAPTTP53KLK7 | |
| SCHEMBL20487094 | 0.81 | MEN1 (0.71) | MEN1KMT2AMAPTKLK7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621672-A | Cyclic sulfonamide compounds and methods of use thereof | 组装生物科学股份有限公司 | 2019-12-27 | — | — | CN | disclosed |