⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355647 | 0.72 | — | — | |
| SCHEMBL1558889 | 0.69 | — | — | |
| SCHEMBL6242643 | 0.69 | — | — | |
| SCHEMBL27721707 | 0.69 | — | — | |
| SCHEMBL7171317 | 0.67 | — | — | |
| SCHEMBL5075134 | 0.67 | — | — | |
| SCHEMBL28224722 | 0.67 | — | — | |
| Phosphine SCHEMBL4667232 | 0.67 | — | — | |
| SCHEMBL10962994 | 0.65 | TSHR (0.32) | — | |
| SCHEMBL3840749 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516965-A | A kind of synthetic method of TGDDM epoxy resin | 西安元创化工科技股份有限公司 | 2019-03-26 | — | — | CN | claimed |
| US-12448392-B2 | Spiropiperidine derivatives | CEPHALON LLC (US) | 2025-10-21 | — | — | US | disclosed |
| US-20240166661-A1 | Spiropiperidine Derivatives | CEPHALON LLC | 2024-05-23 | — | — | US | disclosed |
| US-11878982-B2 | Spiropiperidine derivatives | 89BIO LTD (IL) | 2024-01-23 | — | — | US | disclosed |
| US-20210284651-A1 | Spiropiperidine Derivatives | CEPHALON LLC | 2021-09-16 | — | — | US | disclosed |
| US-11046707-B2 | Spiropiperidine derivatives | 89BIO LTD (IL) | 2021-06-29 | — | — | US | disclosed |
| US-20200031840-A1 | SPIROPIPERIDINE DERIVATIVES | CEPHALON LLC | 2020-01-30 | — | — | US | disclosed |
| CN-109516965-A | A kind of synthetic method of TGDDM epoxy resin | 西安元创化工科技股份有限公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-109516965-A | A kind of synthetic method of TGDDM epoxy resin | 西安元创化工科技股份有限公司 | 2019-03-26 | — | — | CN | disclosed |
| EP-2342182-B1 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2012-11-14 | — | — | EP | disclosed |
| US-8242134-B2 | Isoquinolinone derivatives as NK3 antagonists | H. LUNDBECK A/S (DK) | 2012-08-14 | — | — | US | disclosed |
| US-20100076016-A1 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS | H. LUNDBECK A/S (DK) | 2010-03-25 | — | — | US | disclosed |