Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474917 | 0.92 | S1PR1 (0.35) | S1PR1S1PR3MTNR1AHDAC3HDAC2 | |
| SCHEMBL13262601 | 0.90 | S1PR1 (0.34) | S1PR1S1PR3 | |
| SCHEMBL2473567 | 0.87 | — | — | |
| SCHEMBL2473069 | 0.82 | S1PR1 (0.38) | S1PR1S1PR3HDAC3HDAC2HDAC1 | |
| SCHEMBL13262791 | 0.82 | S1PR1 (0.33) | S1PR1S1PR3 | |
| SCHEMBL16503787 | 0.82 | S1PR1 (0.33) | S1PR1S1PR3 | |
| SCHEMBL2470384 | 0.80 | S1PR1 (0.43) | S1PR1S1PR3 | |
| SCHEMBL2472957 | 0.80 | S1PR1 (0.35) | S1PR1S1PR3 | |
| SCHEMBL2472812 | 0.79 | S1PR1 (0.39) | S1PR1S1PR3HDAC3HDAC2HDAC1 | |
| SCHEMBL2472576 | 0.77 | S1PR1 (0.40) | S1PR1S1PR3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110311485-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE | ALMIRALL S.A. (ES) | 2011-12-22 | — | — | US | disclosed |
| WO-2010072352-A1 | 1, 2, 4 -OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE | ALMIRALL S.A. (ES) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110311485-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE | S1PR1, S1PR2, S1PR3 | S1PR1 1/4885S1PR3 3/4885MTNR1A 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.