Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28340811 | 1.00 | POLB (0.65) | POLBHTTTDP1HDAC6HDAC3 | |
| SCHEMBL28343342 | 0.90 | POLB (0.61) | POLBHTTTDP1HDAC6HDAC3 | |
| SCHEMBL28343327 | 0.89 | POLB (0.60) | POLBHTTTDP1HDAC6HDAC3 | |
| SCHEMBL28340849 | 0.88 | POLB (0.68) | POLBHTTTDP1HDAC6HDAC3 | |
| SCHEMBL28340819 | 0.86 | POLB (0.63) | POLBHTTTDP1HDAC6HDAC3 | |
| SCHEMBL28340820 | 0.86 | POLB (0.63) | POLBHTTTDP1HDAC6HDAC3 | |
| SCHEMBL28343354 | 0.86 | POLB (0.57) | POLBHTTTDP1HDAC6HDAC3 | |
| SCHEMBL28340832 | 0.86 | POLB (0.57) | POLBHTTTDP1HDAC6HDAC3 | |
| SCHEMBL28343353 | 0.86 | POLB (0.57) | POLBHTTTDP1HDAC6HDAC3 | |
| SCHEMBL28340831 | 0.86 | POLB (0.57) | POLBHTTTDP1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627717-B | Branched 1, 4-diene amide derivative and synthesis method thereof | 杭州师范大学 | 2021-01-26 | — | — | CN | disclosed |
| CN-110627717-A | Branched 1, 4-diene amide derivative and synthesis method thereof | 杭州师范大学 | 2019-12-31 | — | — | CN | disclosed |