Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.44 |
| ▸ | FLT3 | P36888 | 6/20 | 0.44 |
| ▸ | KIT | P10721 | 3/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16029254 | 0.86 | CSF1R (0.59) | CSF1RPDGFRAFLT3KITPDGFRB | |
| SCHEMBL16028387 | 0.79 | CSF1R (0.57) | CSF1RPDGFRAFLT3KITPDGFRB | |
| SCHEMBL30086819 | 0.79 | CSF1R (0.57) | CSF1RPDGFRAFLT3KITPDGFRB | |
| SCHEMBL30086983 | 0.78 | CSF1R (0.59) | CSF1RPDGFRAFLT3KITPDGFRB | |
| SCHEMBL21426311 | 0.78 | CSF1R (0.59) | CSF1RPDGFRAFLT3KITPDGFRB | |
| SCHEMBL16027980 | 0.77 | CSF1R (0.46) | CSF1RPDGFRAFLT3KITPDGFRB | |
| SCHEMBL16028875 | 0.77 | CSF1R (0.55) | CSF1RPDGFRAFLT3KITPDGFRB | |
| SCHEMBL25268987 | 0.73 | KDR (0.52) | CSF1RPDGFRAFLT3KITPDGFRB | |
| SCHEMBL30086962 | 0.73 | KDR (0.52) | CSF1RPDGFRAFLT3KITPDGFRB | |
| SCHEMBL16029505 | 0.72 | CSF1R (0.61) | CSF1RPDGFRAFLT3KITPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563700-A | N-acyl-N' - (pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activity | 德西费拉制药有限责任公司 | 2019-12-13 | — | — | CN | disclosed |