Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 15/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30353569 | 1.00 | ADORA1 (0.53) | ADORA1RPS6KA3KMT2AADORA2AADORA2B | |
| SCHEMBL30353590 | 0.89 | ADORA1 (0.45) | ADORA1RPS6KA3KMT2AADORA2A | |
| SCHEMBL28342652 | 0.89 | ADORA1 (0.45) | ADORA1RPS6KA3KMT2AADORA2A | |
| SCHEMBL21621288 | 0.84 | ADORA1 (0.55) | ADORA1RPS6KA3KMT2AADORA2A | |
| SCHEMBL29947057 | 0.84 | ADORA1 (0.55) | ADORA1RPS6KA3KMT2AADORA2A | |
| SCHEMBL28342682 | 0.82 | ADORA1 (0.54) | ADORA1RPS6KA3KMT2AADORA2A | |
| SCHEMBL30353580 | 0.82 | ADORA1 (0.54) | ADORA1RPS6KA3KMT2AADORA2A | |
| SCHEMBL30353593 | 0.80 | ADORA1 (0.36) | ADORA1RPS6KA3KMT2AADORA2AADORA2B | |
| SCHEMBL28342708 | 0.80 | ADORA1 (0.36) | ADORA1RPS6KA3KMT2AADORA2AADORA2B | |
| SCHEMBL30353598 | 0.80 | ADORA1 (0.50) | ADORA1RPS6KA3KMT2AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110655509-B | 2-aminopyrimidine derivatives, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-110655509-A | 2-aminopyrimidine derivatives, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2020-01-07 | — | — | CN | disclosed |