Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14471468 | 0.82 | HSP90AA1 (0.43) | CASP6MEN1PSMD14PRKACAKMT2A | |
| SCHEMBL13398588 | 0.82 | HSD17B10 (0.47) | CASP6MEN1PSMD14PRKACAKMT2A | |
| SCHEMBL994671 | 0.82 | MPL (0.44) | CASP6MEN1PSMD14PRKACAKMT2A | |
| SCHEMBL7014963 | 0.82 | HSD17B10 (0.44) | CASP6MEN1PSMD14PRKACAKMT2A | |
| SCHEMBL2312779 | 0.81 | EIF4E (0.44) | CASP6MEN1PSMD14PRKACAKMT2A | |
| SCHEMBL4059206 | 0.78 | MEN1 (0.52) | CASP6MEN1PSMD14PRKACAKMT2A | |
| SCHEMBL28345040 | 0.75 | ADORA2A (0.36) | MEN1KMT2AGAAL3MBTL1ALDH1A1 | |
| Benzene SCHEMBL6392611 | 0.74 | TDP1 (0.40) | CASP6MEN1PSMD14PRKACAKMT2A | |
| SCHEMBL21623742 | 0.73 | TDP1 (0.42) | CASP6MEN1PSMD14PRKACAKMT2A | |
| SCHEMBL4050005 | 0.73 | ADORA2A (0.47) | MEN1KMT2AALDH1A1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118059093-A | Inhibitors of short chain dehydrogenase activity for the treatment of fibrosis | 卡斯西部储备大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-110582277-B | Inhibitors of short-chain dehydrogenase activity for promoting neurogenesis and inhibiting neuronal cell death | 卡斯西部储备大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-110582277-A | Inhibitors of short chain dehydrogenase activity for promoting neurogenesis and inhibiting neuronal cell death | 卡斯西部储备大学 | 2019-12-17 | — | — | CN | disclosed |