Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30309428 | 1.00 | NR4A2 (0.81) | NR4A2KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL408819 | 0.90 | NR4A2 (1.00) | NR4A2KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL5101006 | 0.85 | NR4A2 (0.59) | NR4A2KDM4EALDH1A1LMNATSHR | |
| SCHEMBL5100563 | 0.83 | KDM4E (0.61) | NR4A2KDM4ELMNA | |
| SCHEMBL30309433 | 0.83 | KDM4E (0.61) | NR4A2KDM4ELMNA | |
| Acetaldehyde SCHEMBL5095402 | 0.81 | NR4A2 (0.55) | NR4A2KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL28666457 | 0.81 | NR4A2 (0.79) | NR4A2KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL30615755 | 0.81 | NR4A2 (0.56) | NR4A2KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL16285135 | 0.81 | NR4A2 (0.56) | NR4A2KDM4EALDH1A1LMNA | |
| SCHEMBL27868258 | 0.81 | NR4A2 (0.56) | NR4A2KDM4EALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642837-B | Pyridine amide compound containing triazole or quinolinone structure and application thereof | 江西科技师范大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-110642837-A | Pyridine amide compound containing triazole or quinolinone structure and application thereof | 江西科技师范大学 | 2020-01-03 | — | — | CN | disclosed |