Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.60 |
| ▸ | AKT2 | P31751 | 2/20 | 0.60 |
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | JAK3 | P52333 | 10/20 | 0.55 |
| ▸ | JAK1 | P23458 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345597 | 0.87 | DOT1L (0.66) | JAK3 | |
| SCHEMBL29436071 | 0.86 | KIT (0.66) | KITAKT2GSK3BLCKJAK3 | |
| SCHEMBL15664244 | 0.84 | KIT (0.68) | KITAKT2GSK3BLCKJAK3 | |
| SCHEMBL15664428 | 0.83 | KIT (0.67) | KITAKT2GSK3BLCKJAK3 | |
| SCHEMBL15663627 | 0.82 | KIT (0.60) | KITAKT2GSK3BLCKJAK3 | |
| SCHEMBL15664424 | 0.81 | JAK3 (0.60) | KITAKT2GSK3BLCKJAK3 | |
| SCHEMBL9967045 | 0.81 | KIT (0.65) | KITAKT2GSK3BLCKJAK3 | |
| SCHEMBL15664101 | 0.81 | KIT (0.67) | KITAKT2GSK3BLCKJAK3 | |
| SCHEMBL9967220 | 0.80 | JAK3 (0.58) | KITAKT2GSK3BLCKJAK3 | |
| SCHEMBL9967160 | 0.80 | JAK3 (0.61) | KITAKT2GSK3BLCKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105712998-B | Azaindole derivatives, preparation method and medical application thereof | 上海润诺生物科技有限公司 | 2019-12-13 | — | — | CN | disclosed |