Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12534047 | 1.00 | IDO1 (0.60) | IDO1GPR84KDM4EMEN1KMT2A | |
| SCHEMBL19054699 | 0.88 | IDO1 (0.55) | IDO1GPR84KDM4EMEN1KMT2A | |
| SCHEMBL18856897 | 0.86 | IDO1 (0.57) | IDO1GPR84KDM4EMEN1KMT2A | |
| SCHEMBL21549462 | 0.85 | IDO1 (0.53) | IDO1GPR84KDM4EMEN1KMT2A | |
| SCHEMBL29308304 | 0.83 | IDO1 (0.54) | IDO1GPR84KDM4EMEN1KMT2A | |
| SCHEMBL820361 | 0.82 | IDO1 (0.61) | IDO1GPR84KDM4EMEN1KMT2A | |
| SCHEMBL8416938 | 0.82 | IDO1 (0.61) | IDO1GPR84KDM4EMEN1KMT2A | |
| SCHEMBL6655810 | 0.82 | IDO1 (0.53) | IDO1GPR84KDM4EMEN1KMT2A | |
| SCHEMBL6655804 | 0.82 | IDO1 (0.53) | IDO1GPR84KDM4EMEN1KMT2A | |
| SCHEMBL9275412 | 0.82 | KDM4E (0.74) | IDO1GPR84KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110655456-B | Method for preparing chiral alkyl compound by asymmetric catalytic hydrogenation of E/Z mixed or single-configuration tri-substituted olefin | 浙江大学 | 2020-11-24 | — | — | CN | disclosed |
| CN-110655456-A | Method for preparing chiral alkyl compound by asymmetric catalytic hydrogenation of E/Z mixed or single-configuration tri-substituted olefin | 浙江大学 | 2020-01-07 | — | — | CN | disclosed |