Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30335327 | 1.00 | MAP4K4 (0.49) | MAP4K4CYP1A2GAACYP2C9PKM | |
| SCHEMBL28347123 | 1.00 | MAP4K4 (0.49) | MAP4K4CYP1A2GAACYP2C9PKM | |
| SCHEMBL11211716 | 0.84 | MAP4K4 (0.50) | MAP4K4CYP1A2GAACYP2C9PKM | |
| SCHEMBL11177411 | 0.84 | CYP1A2 (0.54) | MAP4K4CYP1A2GAACYP2C9PKM | |
| SCHEMBL135587 | 0.82 | CYP1A2 (0.59) | MAP4K4CYP1A2GAACYP2C9PKM | |
| SCHEMBL3217144 | 0.82 | CYP1A2 (0.59) | MAP4K4CYP1A2GAACYP2C9PKM | |
| Hydrochloric Acid SCHEMBL9362415 | 0.81 | CYP1A2 (0.57) | MAP4K4CYP1A2GAACYP2C9PKM | |
| Hydrochloric Acid SCHEMBL9362257 | 0.81 | CYP1A2 (0.57) | MAP4K4CYP1A2GAACYP2C9PKM | |
| SCHEMBL8900988 | 0.80 | CYP1A2 (0.69) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL11550164 | 0.80 | CYP1A2 (0.69) | CYP1A2GAACYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627782-B | Preparation method and application of pyridyloxy phenoxypropionamide compound containing disulfide bond | 山东胜邦绿野化学有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-110627782-A | Preparation method and application of pyridyl phenoxyl propionamide compound containing disulfide bond | 杨子辉 | 2019-12-31 | — | — | CN | claimed |
| CN-110627782-B | Preparation method and application of pyridyloxy phenoxypropionamide compound containing disulfide bond | 山东胜邦绿野化学有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-110627782-A | Preparation method and application of pyridyl phenoxyl propionamide compound containing disulfide bond | 杨子辉 | 2019-12-31 | — | — | CN | disclosed |