SCHEMBL28347221

SCHEMBL28347221

Nc1cccc(C(=O)c2cccc(Oc3ccccc3)c2)c1N

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.57
GAA P10253 1/20 0.51
MAPT P10636 1/20 0.51
HDAC8 Q9BY41 2/20 0.51
ESRRA P11474 1/20 0.51
NPC1 O15118 1/20 0.49
TNKS O95271 1/20 0.49
PARP15 Q460N3 1/20 0.49
PARP14 Q460N5 1/20 0.49
PARP10 Q53GL7 1/20 0.49
TNKS2 Q9H2K2 1/20 0.49
PARP2 Q9UGN5 1/20 0.49
ERCC5 P28715 1/20 0.48
FEN1 P39748 1/20 0.48
POLB P06746 1/20 0.46
STS P08842 1/20 0.46
MAOB P27338 1/20 0.45
HDAC3 O15379 1/20 0.44
BRAF P15056 1/20 0.44
HDAC4 P56524 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30055559 1.00 AKR1C3 (0.57) AKR1C3GAAMAPTHDAC8ESRRA
SCHEMBL28919454 0.87 AKR1C3 (0.55) AKR1C3GAAMAPTHDAC8ESRRA
SCHEMBL29361426 0.87 AKR1C3 (0.55) AKR1C3GAAMAPTHDAC8ESRRA
SCHEMBL22444374 0.83 AKR1C3 (0.54) AKR1C3HDAC8NPC1TNKSPARP15
SCHEMBL28349997 0.82 SRD5A2 (0.62) MAOBSIRT2
SCHEMBL29786713 0.82 MAPT (0.74) AKR1C3GAAMAPTPOLB
Benzene SCHEMBL28303083 0.82 MAPT (0.74) AKR1C3GAAMAPTPOLB
SCHEMBL112508 0.82 MAPT (0.74) AKR1C3GAAMAPTPOLB
SCHEMBL28282156 0.81 MAPT (0.71) AKR1C3GAAMAPTPOLB
SCHEMBL28884089 0.81 AKR1C3 (0.51) AKR1C3HDAC8NPC1TNKSPARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110709245-B Laminate of polyimide film and inorganic substrate 东洋纺株式会社 2021-08-06 CN disclosed
CN-107073891-B Laminated polymer film of silane coupling agent layer 东洋纺株式会社 2021-03-16 CN disclosed
CN-110709245-A Laminate of polyimide film and inorganic substrate 东洋纺株式会社 2020-01-17 CN disclosed