SCHEMBL28347779

SCHEMBL28347779

CC#CC#CC(O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CACNA2D1 P54289 1/20 0.61
CACNB2 Q08289 1/20 0.61
CACNA1C Q13936 1/20 0.61
TSHR P16473 2/20 0.48
ALDH1A1 P00352 4/20 0.42
MAPK1 P28482 2/20 0.42
HTT P42858 1/20 0.41
LMNA P02545 4/20 0.39
ADRA2C P18825 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ADRA2A P08913 1/20 0.38
HIF1A Q16665 1/20 0.38
CHRM2 P08172 1/20 0.35
ADRA1A P35348 1/20 0.35
RGS12 O14924 1/20 0.35
GLA P06280 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9856659 0.89 CACNA2D1 (0.66) CACNA2D1CACNB2CACNA1CTSHRALDH1A1
SCHEMBL96275 0.85 TSHR (0.54) CACNA2D1CACNB2CACNA1CTSHRALDH1A1
SCHEMBL9547891 0.79 TSHR (0.64) CACNA2D1CACNB2CACNA1CTSHRALDH1A1
SCHEMBL25037614 0.76 CACNA2D1 (0.53) CACNA2D1CACNB2CACNA1CTSHRALDH1A1
SCHEMBL2799171 0.75 TSHR (0.48) CACNA2D1CACNB2CACNA1CTSHRALDH1A1
SCHEMBL19254173 0.74 CACNA2D1 (0.55) CACNA2D1CACNB2CACNA1CTSHRALDH1A1
SCHEMBL6931356 0.73 CACNA2D1 (0.50) CACNA2D1CACNB2CACNA1CTSHRALDH1A1
SCHEMBL9619367 0.73 TSHR (0.56) CACNA2D1CACNB2CACNA1CTSHRALDH1A1
SCHEMBL9119346 0.71 TSHR (0.54) CACNA2D1CACNB2CACNA1CTSHRALDH1A1
SCHEMBL23996119 0.71 TSHR (0.54) CACNA2D1CACNB2CACNA1CTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110604762-A Traditional Chinese medicine composition for treating kidney-type infectious bronchitis of poultry and preparation method thereof 临沂金翠兽药有限公司 2019-12-24 CN disclosed