SCHEMBL28348178

SCHEMBL28348178

Cc1ccc2nc(N=Nc3ccc(O)cc3O)sc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.49
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
L3MBTL1 Q9Y468 5/20 0.49
HTT P42858 4/20 0.49
MAPK1 P28482 3/20 0.49
TDP1 Q9NUW8 3/20 0.49
POLB P06746 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KDM4E B2RXH2 1/20 0.47
IDO1 P14902 1/20 0.47
TDO2 P48775 1/20 0.47
GFER P55789 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MCL1 Q07820 1/20 0.44
RAB9A P51151 2/20 0.43
EGFR P00533 1/20 0.42
HSD17B1 P14061 2/20 0.41
HSD17B2 P37059 2/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19519681 0.72 MAPT (0.58) MAPTMEN1KMT2AL3MBTL1HTT
SCHEMBL25925915 0.72 MEN1 (0.54) MAPTMEN1KMT2AL3MBTL1HTT
SCHEMBL12422109 0.71 APP (0.53) MAPTHTTSMN1; SMN2APP
SCHEMBL12422083 0.71 APP (0.53) MAPTMEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL16252392 0.71 MAPT (0.61) MAPTMEN1KMT2AL3MBTL1HTT
SCHEMBL22574540 0.70 MAPT (0.56) MAPTSMN1; SMN2KDM4EGFERNPSR1
SCHEMBL12422466 0.69 APP (0.42) MAPTMEN1KMT2AL3MBTL1SMN1; SMN2
SCHEMBL24693082 0.69 MAPT (0.74) MAPTMEN1KMT2AL3MBTL1HTT
SCHEMBL19736224 0.69 MAPT (0.74) MAPTMEN1KMT2AL3MBTL1HTT
SCHEMBL10819273 0.69 MAPT (0.74) MAPTMEN1KMT2AL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108187824-B turntable type crushing and compressing device for underground sewage treatment engineering and working method thereof XUZHOU INSTITUTE OF TECHNOLOGY (CN) 2019-12-10 CN claimed
CN-108187824-B turntable type crushing and compressing device for underground sewage treatment engineering and working method thereof XUZHOU INSTITUTE OF TECHNOLOGY (CN) 2019-12-10 CN disclosed